Signal Transduction 

• Protein tyrosine phosphorylation in the cell nucleus 
• Role of Hck and related tyrosine kinases in signal transduction 
• Regulation of caspase gene expression by tumour suppressor p53 and Anti cancer drugs 

Transcription 

• Role of nucleosomes and chromatin structure in transcription
• Regulation of transcription by the activator 

Nuclear Pores and Lamins 

• Nuclear transport of proteins 
• Regulation of lamin genes and structural organisation of nuclear lamina 

Host-Guest Interactions in Plants 

• Genetics of plant pathogen interactions 

Enzyme Structure-Function 

• Study of RNAses and RNA degradation in mammalian cells 
• Regulation and genetic engineering of the key enzyme of starch synthesis - ADP glucose pyrophosphorylase (AGPase) in rice 
• Directed evolution of lipase