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R.Sankaranarayanan's Group

Dr.Rajan Sankaranarayanan obtained his M.
Sc. in Physics from Madura College, Madurai Kamaraj University
in 1990 and Ph. D. from the Molecular Biophysics Unit, Indian Institute of Science,
Bangalore in 1996. He was a postdoctoral research fellow in the Institut de Genetique et de
Biologie Moleculaire et Cellulaire (IGBMC), Strasbourg, France
from 1996-2002.
He joined the Centre for Cellular and
Molecular Biology (CCMB), Hyderabad as a senior scientist
in March 2002. He has setup a state-of-the-art macromolecular
crystallography laboratory in the institute and is carrying out
research in the field of Structural Biology. His research interests are
in trying to understand intermolecular recognition mechanisms. One major
area of focus in his laboratory is in elucidating how very similar
substrates are recognized with a high accuracy in order to achieve a
faithful translation of the genetic code. The other areas of research in
his laboratory includes understanding the structural basis of functional
interplay between polyketide synthases and fatty acid synthases in
Mycobacterium tuberculosis, structure-function studies on virulence
factors of a rice pathogenic bacterium and structure-guided design of
thermostable lipases.
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