Despite recent advances in vertebrate model systems, the technology for genetic manipulation in the fruit fly drosophila is by far the most sophisticated. The fly facility has a state-of-the-art set up for maintenance and generation of transgenic flies and a dedicated fly food production unit (Nectar). Apart from constant use by research groups, the facility offers training. The key activities of this facility include the use of genetically modified flies to reveal gene function in development, as well as the use of flies to study the function of genes from other organisms, including human. The function and interaction of disease genes involved in cancer, and neurodegenerative disorders are modeled here, and studies include drug screening for molecules that counteract the effects of specific disease mutations.

For any service/usage of facility, please write to bdg@ccmb.res.in