CSIR - Centre for Cellular & Molecular Biology
Council of Scientific and Industrial Research
Ministry of Science & Technology, Govt. of India
200+ people
Trained in CCMB and other organizations (medical hospitals, universities and research institutes).
Training
The culture is used for vaccine and antisera development, and testing antiviral drugs and sanitization measures
Coronavirus culturing
25 products
have been validated so far at CCMB. 10 more under validation.
Validation of COVID-19 testing kits
Validated by DBT-CDFD and IISER-Berhampur. Preprint published on Jun 1st. Sent recommendations to ICMR on Jun 4th and the office of Principal Scientific Advisor on June 13th. Questions raised by ICMR on July 20th, which were addressed in a day. Approval still awaited from ICMR to use the method as an alternate testing method in India. Published in Oxford Academic Biology Methods & Protocols.
Development of dry swab one-step PCR test for COVID-19
Monoclonal and polyclonal antibodies are in development
Hybridoma preparation for antibodies against SARS COV-2
25000+ samples
have been tested so far at CCMB
Testing
500 genomes
of coronavirus sequenced. >300 submitted to GISAID. Found an uncharacterized population of coronavirus (Clade I/A3i), which had spread but eventually faded away. Finding submitted to bioRxiv. Finds the current prevalent strain in India matches the globally prevalent strain – Clade A2a
Genome sequencing of Coronavirus
Partners with VINS BioProducts, INTEL, IIIT, Bharat Biotech, Syngene among others in developing COVID-19 testing methods and therapeutics
Multiple partnerships with industries
Pilot run in Telangana and Karnataka with (x) number of samples
Development of NGS-based COVID-19 testing
6% of Hyderabad's Population
has shed the coronavirus in the month of July. Finding submitted to medRxiv
Wastewater-based COVID-19 mass surveillance
Trained over 200 people in CCMB and other organizations (medical hospitals, universities and research institutes)
CCMB has tested about 25,000 samples so far.
The culture is used for vaccine and antisera development, and testing antiviral drugs and sanitization measures.
Genomes of ~500 Indian isolates of coronavirus sequenced. >300 submitted to GISAID. Found an uncharacterized population of coronavirus (Clade A3i), which had spread but eventually faded away. Finding submitted to bioRxiv. Finds the current prevalent strain in India matches the globally prevalent strain – Clade A2a.
CCMB has validated 25 products so far. 10 more under validation
Partners with VINS BioProducts, INTEL, IIIT, Bharat Biotech, Syngene among others in developing COVID-19 testing methods and therapeutics.
Validated by DBT-CDFD and IISER-Berhampur. Posted preprint on Jun 1st. Sent recommendations to ICMR on Jun 4th and office of Principal Scientific Advisor on Jun 13th. Questions raised by ICMR on Jul 20 replied in a day. Approval still awaited from ICMR to use the method as an alternate testing method in India. Published in Oxford Academic Biology Methods & Protocols.
Pilot run in Telangana and Karnataka with (x) number of samples
Monoclonal and polyclonal antibodies are in development
Estimates at least 6% of Hyderabad's population has shed the coronavirus in the month of July. Finding submitted to medRxiv.
The Centre for Cellular & Molecular Biology (CCMB) is a premier research organization in frontier areas of modern biology. The objectives of the Centre are to conduct high quality basic research and training in frontier areas of modern biology, and promote centralised national facilities for new and modern techniques in the inter-disciplinary areas of biology.
CCMB was set up initially as a semi-autonomous Centre on April 1, 1977 with the Biochemistry Division of the then Regional Research Laboratory (presently, Indian Institute of Chemical Technology, IICT) Hyderabad forming its nucleus and Dr P M Bhargava heading the new Centre. CCMB moved to its present campus on November 26, 1987.
MoreCCMB conducts exploratory research addressing the fundamental questions in biology. It also seeks to develop technology based on the basic research findings towards the unmet societal needs of the country.
Thesis Title: Exploring additional Genetic factors associated with susceptibility/resistance to malaria among Indian populations
Venue : Director`s Committee Room
Date : 29-01-2021 | Time : 12:00Noon
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