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CSIR - Centre for Cellular & Molecular Biology

Council of Scientific and Industrial Research
Ministry of Science & Technology, Govt. of India

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Amitabha Chattopadhyay

SERB Distinguished Fellow
Email: amit@ccmb.res.in
Phone: +91-040-27192578

Research Interests

The major research interest of our group is centered on membrane and receptor biology using a variety of biophysical, biochemical and cell biological approaches. Fluorescence-based spectroscopic and microscopic approaches are extensively used in our laboratory. The research interest of our group can be broadly categorized as follows:

  • Membrane Organization and Dynamics using the Wavelength-Selective Fluorescence Approach.
  • Novel Organization of Cholesterol in Membranes at Low Concentrations: Effects of Curvature Stress and Membrane Thickness.
  • Organization, Dynamics and Lipid-protein Interactions of the Serotonin1A (5-HT1A) Receptor.
  • Monitoring Organization and Dynamics of the Serotonin1A (5-HT1A) Receptor in Live Cells utilizing Dynamic Fluorescence Microscopy (FRAP and FCS).
  • Role of Membrane Cholesterol in Leishmaniasis.
  • Selected Publications

    Chakraborty, H., and Chattopadhyay, A. (2015) `Excitements and Challenges in GPCR Oligomerization: Molecular Insight from FRET` (invited review) ACS Chem. Neurosci. 6: 199-206.

    Viswanathan, G., Jafurulla, M., Kumar, G.A., Raghunand, T.R., and Chattopadhyay, A. (2015) `Dissecting the Membrane Cholesterol Requirement for Mycobacterial Entry into Host Cells` Chem. Phys. Lipids 189: 19-27.

    Chattopadhyay, A., and Haldar, S. (2014) `Dynamic Insight into Protein Structure utilizing Red Edge Excitation Shift` Acc. Chem. Res. 47: 12-19.

    Ganguly, S., Clayton, A.H.A., and Chattopadhyay, A. (2011) `Organization of Higher Order Oligomers of the Serotonin1A Receptor Explored utilizing Homo-FRET in Live Cells` Biophys. J. 100: 361-368.

    Shrivastava, S., Pucadyil, T.J., Paila, Y.D., Ganguly, S., and Chattopadhyay, A. (2010) `Chronic Cholesterol Depletion using Statin Impairs the Function and Dynamics of Human Serotonin1A Receptors` Biochemistry 49: 5426-5435.

    Education & Experiance

    Patents


    Publications

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    Amitabha Chattopadhyay

    SERB Distinguished Fellow

    2578

    amit@ccmb.res.in

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    Aritri Dutta

    Research Associate

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    Amrita Samanta

    Research Associate-I (DBT)

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    Bhagyashree D Rao

    Senior Research Fellow

    2571

    bhagyashree@ccmb.res.in

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    Aditya Kumar G

    Senior Research Fellow

    2623

    adityakumar@ccmb.res.in

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    Sreetama Pal

    Senior Research Fellow

    2623

    sreetama@ccmb.res.in

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    Parijat Sarkar

    Senior Research Fellow

    2571

    parijat@ccmb.res.in

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    Ashwani Sharma

    Junior Research Fellow

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    Subhashree S Sahu

    Junior Research Fellow

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    Sarosh N. Fatakia

    Visiting Scientist