First slide
Research Interests

Our group is interested in understanding the genetic basis of complex disorders such as type 2 diabetes mellitus and chronic pancreatitis and its interaction with various environmental factors (epigenetic basis). The major focus is on identifying various genetic and nutritional factors (and interaction between them), which influence The Thin Fat Indian Phenotype, and various intermediate traits that predict higher risk of developing diabetes and metabolic syndrome. These determinants could be both maternal and fetal in origin and we believe that the variable clinical phenotype of these complex disorders in Indians has different genetic basis that is regulated differently and is programmed in-utero (Developmental Origins of Adult Common Diseases,). The larger goal is to have comprehensive knowledge of gene-gene and gene-nutrient interaction that will enable to alleviate and/or modulate the clinical course and complications of these disorders by modification of life style and diet, especially micronutrients.

Selected Publications

C S Yajnik, G R Chandak, C Joglekar, P Katre, D S Bhat, S N Singh, C S Janipalli, H Refsum, G Krishnaveni, S Veena, C Osmond, CHD Fall. Maternal homocysteine in pregnancy and offspring birthweight: Epidemiological associations and Mendelian randomizationanalysis. Int J Epidemiology 22 July 2014. Epub ahead of print. PMID: 25052622. 
[Accompanied by Editorial Commentary, Sarah J Lewis (2014). "One-carbon metabolism has major implications for fetal growth and development beyond neural tube defects" Int. J. of Epidemiol., 1-2 doi: 10.1093/ije/dyu175].

Heiko Witt, Sebastian Beer, Jonas Rosendahl, Jian-Min Chen, GirirajRatanChandak, et al. Loss-of-function mutations in CPA1 are strongly associated with early-onset chronic pancreatitis. Nature Genetics 2013 Oct;45(10):1216-20. doi: 10.1038/ng.2730. Epub 2013 Aug 18.

Ganesh Chauhan, Charles J Spurgeon, 12 more authors and G R Chandak (2010). Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC3018, HHEX, CDKN2A, IGF2BP2 AND CDKAL1 on the risk of type 2 diabetes in 5148 Indians. Diabetes ;59(8):2068-74.

P D Gluckman, P Bateson, A S Beedle, Z A Bhutta, M A Hanson, C Law, K V Anokhin, P Bougneres, G R Chandak, P Dasupta, G D Smith, P T Ellison, T Forrester, S F Gilbert, E Jablonka, H Kaplan, A M Prentice, S J Simpson, R Uauy & M J West-Eberhard (2009)."Development and human disease - a synthesis of evolutionary, medical, anthropological, and economic perspectives". Lancet 373(9675):1654-1657.


G R Chandak, C S Janipalli, S Bhaskar, S R Kulkarni, P Mohankrishna, A T Hattersley, T M Frayling, C S Yajnik (2007). Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population. Diabetologia50(1):63-67. 
[This paper is accompanied by an Editorial Commentary, Zeggini E and McCarthy MI "TCF7L2: the biggest story in diabetes genetics since HLA ?" Diabetologia 50: 1-4.]

Education & Experiance

P.G: Biochemistry ; Banaras Hindu University ; 1993
Ph.D: Genetic basis of tropical calcific pancreatitis ; Osmania University ; 2009
Post.Doc:

Disease Genomics ; CSIR-CCMB ; 1994-96

Experience:

2016 onwards Scientist F Centre for Cellular and Molecular Biology, Hyderabad, India 2015-2016 Director(On lien) Centre for DNA Fingerprinting & Diagnostics, Hyderabad, India 2011-2015 Scientist F Centre for Cellular and Molecular Biology, Hyderabad, India 2006-2011 Scientist EII Centre for Cellular and Molecular Biology, Hyderabad, India 2003-2006 Scientist EI (Merit) Centre for Cellular and Molecular Biology, Hyderabad, India 1999-2003 Scientist C Centre for Cellular and Molecular Biology, Hyderabad, India 1996-1999 Scientist III Centre for DNA Fingerprinting & Diagnostics, Hyderabad, India

Patents

InventionCountries of filing the patentApplication numberPublication numberStatusGrant Number
A kit for detection of mutations causing genetic disorders using unprocessed blood or dried blood spot PCT PCT/IN2020/050189 Filed Under process
A kit for detection of mutations causing genetic disorders using unprocessed blood or dried blood spot India 201911038617 Filed Under process

Publications

TitleJournalYear
Effect of maternal preconceptional and pregnancy micronutrient interventions on children`s DNA methylation: findings from the EMPHASIS study Americal Journal of Clinical Nutrition (Accepted) 2020
Causal relationships between lipid and glycemic levels in an Indian population: A bidirectional Mendelian randomization approach PLoS One (Accepted) PLoS One. 2020 Jan 29;15(1):e0228269. doi: 10.1371/journal.pone.0228269. eCollection 2020. 2020
Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring Molecular and Cellular Biochemistry, 468(1), 83-96 doi: 10.1007/s11010-020-03713-x 2020
Type 1 diabetes genetic risk score is discriminative of diabetes in non-Europeans: evidence from a study in India Scientific Reports (Accepted) 2020
Periconceptional environment predicts leukocyte telomere length in a cross-sectional study of 7-9 year old rural Gambian children Scientific Reports 2020
Novel p.P298L SURF1 mutation in thiamine deficient Leigh syndrome patients compromises cytochrome c oxidase activity Mitochondrion. 2020 May 4. pii: S1567-7249(19)30351-4. doi: 10.1016/j.mito.2020.04.009. 2020
Protease-sensitive pancreatic lipase (PNLIP) variants are associated with early onset chronic pancreatitis Am J Gastroenterol, doi: 10.14309/ajg. 0000000000000051. 2019
Effects of autozygosity on a broad range of human phenotypes Nature Communications (Accepted) 2019
Environmentally sensitive hotspots in the methylome of the early human embryo bioRXiv 2019
The REVAMP study: research exploring various aspects and mechanisms in preeclampsia: study protocol. BMC Pregnancy Childbirth. 2019 Aug 23;19(1):308. doi: 10.1186/s12884-019-2450-0. 2019
Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data (Nature Group). Sci Data., 23;5:180002. doi: 10.1038/sdata.2018.2. 2018
Identification and Characterization of cis-Regulatory Elements "Insulator and Repressor " in PPARD Gene Epigenomics,doi: 10.2217/epi-2017-0139. [Epub ahead of print] 2018
Candidate genes linking maternal nutrient exposure to offspring health via DNA methylation: a review of existing evidence in humans with specific focus on one-carbon metabolism International Journal of Epidemiology (Accepted) 2018
Protease-sensitive pancreatic lipase (PNLIP) variants are associated with early onset chronic pancreatitis American Journal of Gastroenterology (Accepted) 2018
Diet Candidate genes linking maternal nutrient exposure to offspring health via DNA methylation: a review of existing evidence in humans with specific focus on one-carbon metabolism International Journal of Epidemiology, 2018, 1910 2018
GWAS Identifies Population Specific New Regulatory Variants in FUT6 Associated with Plasma B12 Concentrations in Indians. Hum Mol Genet. 2017 Feb 27. doi: 10.1093/hmg/ddx071. 2017
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. 2017 Mar 24. pii: db161329. doi: 10.2337/db16-1329 2017
Hypermethylated CpG sites in the MTR Gene Promoter in Preterm Placenta Epigenomics. 2017 Jul;9(7):985-996. doi: 10.2217/epi-2016-0173. Epub 2017 Jun 15. 2017
Identification of a Functional Enhancer Variant within the Chronic Pancreatitis-Associated SPINK1 c.101A>G (p.Asn34Ser)-Containing Haplotype Hum Mutat. 2017 Aug;38(8):1014-1024. doi: 10.1002/humu.23269. Epub 2017 Jun 15. 2017
Protocol for the EMPHASIS study; epigenetic mechanisms linking maternal pre-conceptional nutrition and children`s health in India and Sub-Saharan Africa. BMC Nutrition (Accepted) 2017
Vitamin B12 Supplementation Influences Methylation of Genes Associated with Type 2 Diabetes & its Intermediate Traits. Epigenomics (Accepted) 2017
Identification and Characterization of cis-Regulatory Elements "Insulator and Repressor " in PPARD Gene Epigenomics (Accepted) 2017
Association Analysis of PRSS1-PRSS2 and CLDN2-MORC4 Variants in Nonalcoholic Chronic Pancreatitis Using Tropical Calcific Pancreatitis as Model. Pancreas, Sep;45(8):1153-7. doi: 10.1097/MPA.0000000000000608. 2016
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function Nat Commun. 2016 Jan 21;7:10023. doi: 10.1038/ncomms10023 2016
Lack of replication of association of THSD7A with obesity. Int J Obes (Lond). 2016 Feb 23. doi: 10.1038/ijo.2016.15. [Epub ahead of print] 2016
No Association Between CEL-HYB Hybrid Allele and Chronic Pancreatitis in Asian Populations Gasteroenterology,150(7):1558-1560.e5. doi: 10.1053/j.gastro.2016.02.071. Epub 2016 Mar 3. 2016
The genetic architecture of type 2 diabetes Nature, 536(7614):41-7. 2016
Birth size, risk factors across life and cognition in late life: Protocol of prospective longitudinal follow-up of the MYNAH (MYsore studies of Natal effects on Ageing and Health) cohort. BMJ Open (Accepted for publication) 2016
Evolution of Phenotypic and Genetic Profile of Tropical Calcific Pancreatitis(Book Chapter) Evolution of Phenotypic and Genetic Profile of Tropical Calcific Pancreatitis(Book Title), Springer(Accepted) 2016
New genetic loci link adipose and insulin biology to body fat distribution Nature (2015 Feb 12;518(7538):187-96. doi: 10.1038/nature14132) 2015
Genetic studies of body mass index yield new insights for obesity biology Nature (2015 Feb 12;518(7538):197-206. doi: 10.1038/nature14177) 2015
New insights from monogenic diabetes for "common" type 2 diabetes Frontiers in Genetics, 6:251. doi: 10.3389/fgene.2015.00251. 2015
Maternal micronutrient deficiency leads to alteration in the kidney proteome in rat pups. Journal of Proteomics, 127(Pt A):178-84. doi: 10.1016/j.jprot.2015.04.035. 2015
Directional dominance on stature and cognition in diverse human populations. Nature. 2015 Jul 23;523(7561):459-62. doi: 10.1038/nature14618. Epub 2015 Jul 1. 2015
Intrauterine Programming of Diabetes and Adiposity. Curr Obes Rep. (4):418-28. doi: 10.1007/s13679-015-0175-6. 2015
Associations of genetic variants in/near BMI-associated genes with type 2 diabetes: A systematic Clin Endocrinol (Oxf). 2014 Nov;81(5):702-10. doi: 10.1111/cen.12428. Epub 2014 Mar 13. 2014
FTO gene variant and risk of hypertension: a meta-analysis of 57,464 hypertensive cases and 41,256 controls Metabolism. 2014 May;63(5):633-9. doi: 10.1016/j.metabol.2014.02.008. Epub 2014 Feb 17. 2014
Altered methylation and expression patterns of genes regulating placental angiogenesis in preterm pregnancy Reprod Sci. 2014 Dec;21(12):1508-17. doi: 10.1177/1933719114532838. Epub 2014 May 6. 2014
Maternal homocysteine in pregnancy and offspring birthweight:Epidemiological associations and Mendelian randomization analysis Int J Epidemiol. 43(5):1487-97. doi: 10.1093/ije/dyu132. Epub 2014 Jul 22. 2014
Association of common genetic variants with lipid traits in the Indian population PLoS One. 2014 Jul 3;9(7):e101688. doi: 10.1371/journal.pone.0101688. eCollection 2014. 2014
Genetic and Phenotypic Heterogeneity in Tropical Calcific Pancreatitis World Journal of Gastroenterology, Dec 14;20(46):17314-23. doi: 10.3748/wjg.v20.i46.17314 2014
Chronic Maternal Vitamin B12 Restriction Induced Changes In Body Composition & Glucose Metabolism In The Wistar Rat Offspring Are Partly Correctable By Rehabilitation PLoS One. 2014 Nov 14;9(11):e112991. doi: 10.1371/journal.pone.0112991. eCollection 2014. 2014
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus PLOS Genetics | DOI:10.1371/journal.pgen.1004876 January 27, 2015 2014
Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children PLoS One. 2013;8(2):e56472. doi: 10.1371/journal.pone.0056472. Epub 2013 Feb 12. 2013
Migration and DNA methylation: a comparison of methylation patterns in type 2 diabetes Journal of Diabetes Research & Clinical Metabolism;2:6. Epub 2013 Feb 6. 2013
STK39 Polymorphism Is Associated with Essential Hypertension: A Systematic Review and Meta-Analysis. PLoS One. 2013;8(3):e59584. doi: 10.1371/journal.pone.0059584. Epub 2013 Mar 18. 2013
Influence of Obesity on Association Between Genetic Variants Identified by Genome-Wide Association Studies and Hypertension Risk in Chinese Children. Am J Hypertens.26(8):990-6. doi: 10.1093/ajh/hpt046. 2013
Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia. Clin Epigenetics. 2013 Apr 26;5(1):6. doi: 10.1186/1868-7083-5-6. 2013
Variants in CPA1 are strongly associated with early-onset chronic pancreatitis Nat Genet. 2013 Oct;45(10):1216-20. doi: 10.1038/ng.2730. Epub 2013 Aug 18. 2013
PPAR Signalling Pathway is a Key Modulator of Liver Proteome in Pups Born to B12 Deficient Rats J Proteomics. 2013 Oct 8;91:297-308. doi: 10.1016/j.jprot.2013.07.027. Epub 2013 Aug 6. 2013
Association analysis of 32 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs PLoS One. 2013;8(1):e53944. doi: 10.1371/journal.pone.0053944. Epub 2013 Jan 17. 2012
Association of genetic variation in FTO with risk of obesity and type 2 diabetes in up to 96,551 East and South Asians Diabetologia; 55(4):981-95. Epub 2011 Nov 23. 2012
LC-MS/MS analysis of differentially expressed glioblastoma membrane proteome reveals altered calcium signalling and other protein groups of regulatory functions Molecular and Cellular Proteomics, M111.013565. doi: 10.1074/mcp.M111.013565 2012
Maternal Dietary Folate and/or Vitamin B12 Restriction alter body composition (Adiposity) and Lipid Metabolism in Wistar Rat Offspring J Nutr Biochem. 24(1):25-31. doi: 10.1016/j.jnutbio.2012.01.004. 2012
High resolution methylome map of rat indicates role of intragenic DNA methylation in identification of coding region PLoS One;7(2):e31621. Epub 2012 Feb 15 2012
Common variants of SLAMF1 and ITLN1 on 1q21 are associated with type 2 diabetes in Indian population. J Hum Genet;57(3):184-90. doi: 10.1038/jhg.2011.150. Epub 2012 Jan 26. 2012
Comprehensive Screening of Chymotrypsin C (CTRC) Gene in Tropical Calcific Pancreatitis Identifies Novel Variants Gut Online First, May 12, 2012:10.1136/gutjnl-2012-302448. 2012
Common polymorphism near the MC4R gene is associated with type 2 diabetes: Data from meta-analysis of 123,373 individuals Diabetologia;55(10):2660-6 2012
Genetic analysis of an Indian family with members affected with Waardenburg syndrome and Duchenne muscular dystrophy Mol Vis;18:2022-32. Epub 2012 Jul 20. 2012
Association between common polymorphism near the MC4R gene and obesity risk: a systematic review and meta-analysis. PLoS One. 2012;7(9):e45731. doi: 10.1371/journal.pone.0045731. Epub 2012 Sep 25. 2012
Proteins with altered levels in plasma from glioblastoma patients as revealed by iTRAQ-based quantitative proteomic analysis PLoS One;7(9):e46153. doi: 10.1371/journal.pone.0046153. Epub 2012 Sep 28. 2012
Evaluation of seven common lipid associated loci in a large Indian sib pair study Lipids Health Dis. 2012 Nov 14;11:155. doi: 10.1186/1476-511X-11-155. 2012
Association study of 25 type 2 diabetes related loci with measures of obesity in Indian sib pairs PLoS ONE 8(1): e53944.doi:10.1371/journal.pone.0053944 2012
H63D mutation in HFE gene is common in Indians and is associated with the European haplotype. J Genet, 91(2):229-32. 2012
Common Variants in NOD2 and IL23R are not Associated with Inflammatory Bowel Disease in Indian Patients J Gastroenterology Hepatology; 26:694-99 2011
A set of five microsatellite markers linked to F8 gene can detect Hemophilia A carriers across India Haemophilia 17(5):e928-35. 2011
Association of PON1 and APOA5 gene polymorphisms in a cohort of Indian patients having coronary artery disease with and without type 2 diabetes. Genet Test Mol Biomarkers 5(7-8):507-12 2011
Relationship of APOA5, PPAR? and HL gene variants with serial changes in childhood body mass index and coronary artery disease risk factors in young adulthood. Lipids in Health and Dis. 10:68 2011
Associations of FTO and MC4R variants with obesity traits in Indians and the role of rural/urban environment as a possible effect modifier. J Obes 2011:307542. Epub 2011 May 17 2011
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study Hum Mol Genet. 20(11) :2273-84 2011
Assessing the pathological relevance of SPINK1 promoter variants. Eur J Human Genetics 19(10):1066-73 2011
Glioblastoma cell secretome: Proteins secreted by three glioblastoma cell lines reveal 148 non-redundant proteins J Proteomics 74(10):1918-25 2011
Analysis of 32 common susceptibility genetic variants and their combined effect in predicting risk of type 2 diabetes and related traits in Indians. Diabetic Medicine 28, 1–7 2011
Maternal One-Carbon Metabolism, MTHFR and TCN2 Genotype and Neural Tube Defects in India Birth Defects Research Part A: Clinical and Molecular Teratology 91(9):848-56 2011
Genetic variants in novel pathways influence blood pressure and cardiovascular risk Nature 478(7367):103-109 2011
What's There in a Name: Tropical Calcific Pancreatitis and Idiopathic Chronic Pancreatitis in India Gut. Oct 27, 10.1136/gut.2010.228452. 2010
Response to: Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2 and CDKAL1 on the risk of type 2 diabetes in 5164 Indians Diabetes. 59:e16 2010
Impact of common variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2 and CDKAL1 on the risk of type 2 diabetes in 5164 Indians Diabetes. 59:2068-2074 2010
Cardiac Beriberi: Often a Missed Diagnosis J Trop Pediatr. 56(4):284-5. doi: 10.1093/tropej/fmp108. Epub 2009 Nov 24. 2009
Genetic Basis of Tropical Calcific Pancreatitis: Similar Finds, Different Minds Chromosomes to Genome. Ed. Rakesh Kumar Mishra, L & G International Publications Ltd., Bangalore, India, pp 155-175 2009
The G191R variant in PRSS2 gene does not play a role in protection against tropical calcific pancreatitis Gut, 58:881-82 2009
Development and human disease - a synthesis of evolutionary, medical, anthropological, and economic perspectives Lancet, 373:1654-57 2009
Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis World J Gastroenterol, January 21; 15(3): 264-269 2009
FTO Gene Variants are Associated with Type 2 Diabetes but not with Obesity in South Asian Indians Diabetologia, 52: 247-52 2008
TCF7L2 gene polymorphisms do not predict susceptibility to diabetes in tropical calcific pancreatis but may interact with SPINK1 and CTSB mutations in predicting diabetes BMC Med Genet, 16:9(1): 80-86 2008
Genetic landscape of the people of India: a canvas for disease gene exploration J Genet, 87(1): 3-20 2008
High Prevalence of Infantile Encephalitic Beriberi with Overlapping Features of Leigh's Disease Journal of Tropical Pediatrics, 54(5):328-32 2008
Trypsinogen Copy Number Mutations in Patients with Idiopathic Chronic Pancreatitis Clinical Gastroenterology and Hepatology, 6: 82-88 2008
Leigh`s Syndrome: A Case Report The International Journal of Pediatrics and Neonatology, 7(2): 1-14 2007
Evaluation of Genetic Markers linked to Hemophilia A Locus: An Indian Experience Haematologica, 92: 1725-26 2007
Biomarkers and Clinical Genomics: Genetic Disorders and Approaches to their Prevention BioArrays: From Basics to Diagnostics. Ed. Krishnarao Appasani, Humana Press Inc, Totowa, NJ, USA, pp 241-257 2007
Comprehensive screening for reg1alpha gene rules out association with tropical calcific pancreatitis World J Gastroenterol 28;13(44):5938-43 2007
Frequency of primary iron overload and HFE gene mutations (C282Y, H63D and S65C) in chronic liver disease patients in north India World Journal of Gastroenterology, 13(21): 2956-2959 2007
Remarkable variation in the informativeness of RFLP markers linked to hemophilia B locus in Indian population groups: Implication in the strategy for carrier detection Disease Markers, 22: 327-334 2007
Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population Diabetologia, 50: 63-67 2007
Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis BMC Gastroenterol 6: 42-47 2006
Triglyceride altering polymorphisms of the ApoAV gene have very different allele frequencies in India compared to Europeans BMC Medical Genetics, 7: 76-81 2006
A novel mutation in STK11 gene is associated with Peutz-Jeghers Syndrome in Indian patients BMC Medical Genetics, 7: 73-78 2006
Genetic Studies in Chronic Pancreatitis in India Chronic Pancreatitis and Pancreatic Diabetes in India. Eds V Balakrishnan, Harish kumar, S Sudhindran, A G Unnikrishnan, LG Creations, Bangalore, pp 243-260 2006
Juvenile Fibrocalculous Pancreatopathy-A Patient Report Journal of Pediatric Endocrinology & Metabolism, 19: 947-950 2006
Association of Cathepsin B Polymorphisms with Tropical Calcific Pancreatitis Gut, 55: 1270-1275 2006
Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene Lipids Health Dis, 5: 11-16 2006
Analysis of Intron 22 Inversion Mutation of Factor VIII Gene in the Patients with Hemophilia-A in J & K State of India Journal of Capital University of Medical Sciences, 26: 677-680 2005
Genotype-phenotype correlation of 5q13 region genes in Spinal Muscular Atrophy patients from India Experimental and Molecular Medicine, 37: 134-141 2005
The Indian Genome Variation Consortium The Indian Genome Variation database (IGVdb): a project overview Human Genetics, 1: 1-11 2005
Mutations in Anionic Trypsinogen Gene are not associated with Tropical calcific Pancreatitis Gut, 54: 705-707 2005
Absence of PRSS1 Mutations and Association of SPINK1 Trypsin Inhibitor Mutations in Hereditary and Non-Hereditary Chronic Pancreatitis Gut, 53: 722-27 2004
Molecular Pathology of Haemophilia-B: Identification of Five Novel Mutations including a LINE1 Insertion in Indian Patients Haemophilia, 10: 259-263 2004
Dystrophy Gene Deletions in South Indian Duchenne Muscular Dystrophy Patients Ind J Med Sciences, 57: 1-6 2003
Apolipoprotein E and Presenilin-1 Allelic Variation and Alzheimer's Disease in India Human Biology, 74: 683-693 2002
Mutations in Pancreatic Secretory Trypsin Inhibitor (PSTI/SPINK1) rather than Cationic Trypsinogen Gene (PRSS1) are Significantly Associated with Tropical Calcific Pancreatitis J Medical Genetics, 39: 347-351 2002
Pancreatic Cancer in Hereditary Pancreatitis: Consensus Guidelines for Prevention, Screening and Treatment Pancreatology, 1: 416-422 2001
Consensus Statement on Genetic Testing for Hereditary Pancreatitis: Guidelines for Indications, Counselling, Consent and Privacy Issues Pancreatology, 1: 405-415 2001
Sickle Cell Gene Haplotypes in Relli and Thurpu Kapu Populations of Andhra Pradesh Human Biology, 72: 535-540 2000
Some atypical and rare sickle cell gene haplotypes in populations of Andhra Pradesh, India Hum Biol;71(3):333-40 1999
Fetus-in-fetu: a case report with molecular analysis J Pediatr Surg;34(4):641-44 1999
Triplet Repeats in Neurological Disorders Reviews in Neurology, Indian Academy of Neurology. Ed. S M Das, R Borgohain, A K Meena. Pp 39-47 1998

G R Chandak

Chief Scientist

2748

chandakgrc@ccmb.res.in

Seema Bhaskar

Principal Technical Officer

2653

seema@ccmb.res.in

Inder Deo Mali

Lab Assistant-I

2653

P Ashok

Lab Attendant(2)

2653

Amitabh Biswas

Project Consultant

2607

amitabh@ccmb.res.in

Venkateswarlu Bandi

Research Associate-I (Project)

venky@ccmb.res.in

Ajay Deepak Verma

Project SRF/RA

2653

ajaydeepak@ccmb.res.in

Prachand I

Senior Research Fellow

2549

prachand@ccmb.res.in

Ashutosh Singh Tomar

Senior Research Fellow

2607

ashutosh.tomar87@ccmb.res.in

Sara Sajjadi

Senior Research Fellow

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sara.sajjadi@ccmb.res.in

Swati Bayyana

Junior Research Fellow

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swati.bayyana@ccmb.res.in

Sohail Rafik Mansuri

Junior Research Fellow

Alagu Sankareswaran

Junior Research Fellow (Project)

2655

sankareshwaran@ccmb.res.in

Shoma Naskar

Project Assistant-II

2607

shoma@ccmb.res.in

Mobeen Shaik

Project Assistant-II

2607

mobeenshaik@ccmb.res.in

Manisha Arumalla

Project Assistant-II

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manishaa@ccmb.res.in

P S K D B Punya Sri

Project Assistant-I

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Shagufta Tasneem

Project Assistant-I

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Varsha Kolaria

Project Assistant-I

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varshak@ccmb.res.in