Training on Faster COVID-19 Testing
CSIR - Centre for Cellular & Molecular Biology
Council of Scientific and Industrial Research
Ministry of Science & Technology, Govt. of India
Senior Scientist
Email: skumar@ccmb.res.in
Phone: +91-040-27192559
Research Interests
Understanding the T cell and NK cell responses in human diseases, using tools of single cell sequencing, genomics, and cellular biochemistry.
Selected Publications
Sarangi SK, Lande KM, & Kumar S (2023). KIR signaling is regulated by electrostatic interaction of its cytosolic tail with the plasma membrane despite being neutral polyampholyte. Proc. Natl. Acad. Sci. U.S.A. 120, e2212987120.
Kumar S (2018). Natural killer cell cytotoxicity and its regulation by inhibitory receptors. Immunology 154, 383-393.
Kumar S, & Jain S (2018). Immune signaling by supramolecular assemblies. Immunology 155,435-445.
Education & Experience
| P.G: | Biotechnology ; Madurai Kamaraj University ; 2002-2004 |
| Ph.D: | Characterization of the initial steps of amyloid fibril formation by barstar ; National Centre for Biological Sciences, Tata Institute of Fundamental Research ; 2004-2010 |
| Post.Doc: | Immunology ; National Institutes of Health ; 2010-2015 Immunology ; Stanford University ; 2015-2017 |
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| Title | Journal | Year |
|---|---|---|
| Helicobacter pylori enhances HLA-C expression in the human gastric adenocarcinoma cells AGS and can protect them from the cytotoxicity of natural killer cells. | Helicobacter 29, e13069 | 2024 |
| KIR signaling is regulated by electrostatic interaction of its cytosolic tail with the plasma membrane despite being neutral polyampholyte | Proc. Natl. Acad. Sci. U.S.A. | 2023 |
| Natural killer cell cytotoxicity and its regulation by inhibitory receptors | Immunology | 2018 |
| Immune signalling by supramolecular assemblies | Immunology | 2018 |
| Zinc-induced polymerization of killer-cell Ig-like receptor into filaments promotes its inhibitory function at cytotoxic immunological synapses. | Molecular Cell | 2016 |
| A single amino acid change in inhibitory killer cell Ig-like receptor results in constitutive receptor self-association and phosphorylation. | Journal of Immunology | 2015 |
| Mechanisms of amyloid fibril formation by proteins | Current Science | 2010 |
| Conformational conversion may precede or follow aggregate elongation on alternative pathways of amyloid protofibril formation | Journal of Molecular Biology | 2009 |
| Structurally distinct amyloid protofibrils form on separate pathways of aggregation of a small protein. | Biochemistry | 2009 |
| Mechanism of formation of amyloid protofibrils of barstar from soluble oligomers: evidence for multiple steps and lateral | Journal of Molecular Biology | 2007 |
2559
skumar@ccmb.res.in
2612
sitanshukumar@ccmb.res.in
2612
ketakibhagwat@ccmb.res.in
2612
etikala.apoorva@ccmb.res.in
List of provisionally selected candidates against Notif.No:02/2022